I do. But, to be honest, as well I put as much as possible in the initialization, moving as much stuff as possible out of run, just, that didn't mean that I waste resources, or ain't be careful with what my plugs do in init.
And I believe, most developers do so as well.
However, some of you here may know that guitarix provide smooth, gab free preset switching, and we archive that by taking all possibility’s into account. That means, we init "all" plugs on application startup, already loaded plugs will be reused. Also, guitarix is a multi-plugin host, so no jack call to register new clients is needed when change a preset (here pedalboard). That mean, changing a pedalboard in guitarix isn't more then provide a new list of pointers to plugins.
I guess that isn't possible for the MOD, but, maybe a new function were users could select/mark pedalboards for live use, so that the plugs which are supposed to be used for a live gig, could be pre-init/load may be of some use.
I know, it will be nearly the same as using a switchbox, just, it will allow a better organization on screen.