In the linux audio developer community there's been a lot of complaint and argument about skuomorphism. I was against it but have somewhat embraced it as an easy to apply design technique that usually impresses. I don't think its the best way for an efficient workflow, but after fighting it for quite some time I realized many of the most popular plugins are popular because they have an attractive UI which inspires or impresses the users. So I just tried to make something, and there is some skuomorphism in it. I think you can do the same with other UI design patterns, but skuomorphism is easier to get "right."
That said, I often look at my MOD pedalboards and think, "look at all that wasted space."
I'm totally open to any suggestions about my plugins' UI designs. I might not apply the suggestions, but I'll listen to them for sure.